(Easy way to get to safe mode - Start>Run type in msconfig - On the Boot tab, mark the safe boot box under Boot options and restart. You'll have to go back to msconfig to clear safe boot, then reboot a 2nd time, after you try to make the changes to the Registry)
I don't know if this will make any difference but it's what I would try next if I personally had this problem.
The regedit program will not allow me to delete the line.
Just what is the key you're trying to delete?
Thank You all for replies. My problem was solved. There was a program that I could not reinstall. I requested help from the program owners. It took them a long time to send a fix. In the meantime I thought the problem may of been in the registry files. I finally got the fix. I Installed the fix and program now worked.